Saturday, February 26, 2005

TB Rx= quadruple therapy plus liver and onions

Actually, you can hold the onions. The February 2005 issue of Chest published an article taking a very old observation(low cholesterol in tb patients) and decided to do something about it.What they did was a clinical trial involving giving cholesterol rich diet to see if a metric of improvement would occur quicker.Actually a couple of indicators did.By week 2, 8/10 in the treatment group achieved a negative culture while only 1/11 in the control group was negative.The authors also reported that sputum production decreased faster in the treatment group.Since 90% plus of tb patients are sputum negative by 6 mos anyway it is not likely that high fat diet diets for a couple of weeks will add much to the final outcome(and this is the era of outcome research)

5 Comments:

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Anonymous Garden Furniture said...

I am a big fan of surveys but some are carried out with no real goal(I mean help to a patient) in mind, I have come across so many that are done for the sake of the test, the outcome was not an issue just the test.

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